SCHEMBL31728131

SCHEMBL31728131

O=C1CC[C@@H](N2Cc3cc(N4CC5(CCNCC5)C4)ccc3C2=O)C(=O)N1

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 11/20 0.60
▸ IKZF2 Q9UKS7 8/20 0.50
▸ CSNK1A1 P48729 2/20 0.50
▸ WIZ O95785 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20231713 1.00 CRBN (0.60) CRBNIKZF2CSNK1A1WIZ
SCHEMBL30694261 1.00 CRBN (0.60) CRBNIKZF2CSNK1A1WIZ
SCHEMBL30702623 1.00 CRBN (0.60) CRBNIKZF2CSNK1A1WIZ
SCHEMBL30985043 0.94 CRBN (0.58) CRBNIKZF2CSNK1A1WIZ
Trifluoroacetic Acid SCHEMBL31568647 0.92 CRBN (0.54) CRBNIKZF2CSNK1A1
Trifluoroacetic Acid SCHEMBL31727277 0.92 CRBN (0.54) CRBNIKZF2CSNK1A1
SCHEMBL29913937 0.92 CRBN (0.60) CRBN
SCHEMBL22291389 0.92 CRBN (0.60) CRBN
Hydrochloric Acid SCHEMBL31155363 0.91 CRBN (0.59) CRBN
SCHEMBL22498051 0.91 CRBN (0.59) CRBNIKZF2CSNK1A1WIZ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025235363-A1 CYCLIN-DEPENDENT KINASE 4 DEGRADERS BLUEPRINT MEDICINES CORPORATION (US) 2025-11-13 — — WO disclosed
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