Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK4 | P11802 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL31729268 | 0.98 | MAPK1 (0.45) | MAPK1CDK2MEN1KMT2AKCNH2 | |
| SCHEMBL3323448 | 0.72 | HTT (0.42) | MAPK1MEN1KMT2AKCNH2CYP1A2 | |
| SCHEMBL25145638 | 0.71 | CACNA1H (0.42) | HRH3CHEK1 | |
| SCHEMBL25222648 | 0.71 | LCK (0.38) | CDK2MEN1KMT2ACCNT1CDK7 | |
| SCHEMBL31619971 | 0.70 | MAPK1 (0.56) | MAPK1MEN1KMT2AKCNH2CHEK1 | |
| SCHEMBL3321777 | 0.70 | MAPK1 (0.46) | MAPK1MEN1KMT2AKCNH2PIK3CA | |
| SCHEMBL13326586 | 0.68 | CDK2 (0.44) | CDK2HRH3CHEK1FPR3FPR2 | |
| SCHEMBL24529842 | 0.67 | PIK3CA (0.52) | MAPK1KCNH2PIK3CACHEK1PTPN11 | |
| SCHEMBL3328240 | 0.67 | MAPK1 (0.63) | MAPK1CDK2CCNA2SYK | |
| SCHEMBL24529803 | 0.66 | DYRK1A (0.52) | MAPK1KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235298-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING THIAZOLYL DERIVATIVES FOR DEGRADING CERTAIN CYCLIN-DEPENDENT KINASE VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |