Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3172840 | 1.00 | EPHX2 (0.59) | EPHX2KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3178421 | 0.91 | EPHX2 (0.63) | EPHX2KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3178427 | 0.91 | EPHX2 (0.63) | EPHX2KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3179778 | 0.87 | EPHX2 (0.59) | EPHX2KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3181113 | 0.87 | EPHX2 (0.59) | EPHX2KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3181109 | 0.87 | EPHX2 (0.59) | EPHX2KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3178456 | 0.87 | EPHX2 (0.59) | EPHX2KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3179788 | 0.87 | EPHX2 (0.59) | EPHX2KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3178463 | 0.87 | EPHX2 (0.59) | EPHX2KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL3181086 | 0.86 | EPHX1 (0.59) | EPHX2KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | claimed |