Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.39 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11149608 | 0.84 | GABRR1 (0.38) | GABRR1GABRR2BLMTDP1NPSR1 | |
| SCHEMBL8118802 | 0.80 | HCAR2 (0.54) | GABRR1GABRR2BLMTDP1NPSR1 | |
| SCHEMBL4449228 | 0.80 | HCAR2 (0.54) | GABRR1GABRR2BLMTDP1NPSR1 | |
| SCHEMBL28282181 | 0.79 | HCAR2 (0.38) | TDP1NPSR1LMNATSHRHCAR2 | |
| SCHEMBL5831229 | 0.75 | HCAR2 (0.42) | TDP1NPSR1LMNATSHRHCAR2 | |
| SCHEMBL5831133 | 0.73 | HCAR2 (0.41) | TDP1NPSR1TSHRHCAR2TAS1R3 | |
| SCHEMBL544590 | 0.72 | TSHR (0.45) | TDP1NPSR1LMNATSHRCHRM1 | |
| SCHEMBL812314 | 0.72 | CHRM1 (0.31) | TDP1NPSR1TSHRCHRM1AKR1A1 | |
| SCHEMBL10735447 | 0.71 | ATM (0.69) | TDP1NPSR1TSHRHCAR2ATM | |
| SCHEMBL10865162 | 0.71 | MAPT (0.38) | GABRR1GABRR2BLMTDP1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2591045-A1 | STABILIZING COMPOSITION FOR HALOGEN-CONTAINING POLYMERS | Reagens S.p.A. (IT) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004377-A1 | STABILIZING COMPOSITION FOR HALOGEN-CONTAINING POLYMERS | REAGENS S.P.A. (IT) | 2012-01-12 | — | — | WO | disclosed |