Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 4/20 | 0.33 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.33 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728421 | 0.89 | — | — | |
| SCHEMBL31727944 | 0.85 | KHK (0.38) | CLK1EPHB4EIF2AK3MET | |
| SCHEMBL31729173 | 0.84 | CLK1 (0.35) | CLK1EPHB4EIF2AK3PDE5A | |
| SCHEMBL31728566 | 0.80 | HTT (0.32) | — | |
| SCHEMBL31728591 | 0.78 | EIF2AK3 (0.39) | CLK1EPHB4EIF2AK3PDE5A | |
| SCHEMBL31727929 | 0.77 | KHK (0.37) | CLK1EPHB4EIF2AK3PDE5AMET | |
| SCHEMBL31728213 | 0.75 | EIF2AK3 (0.38) | CLK1EPHB4EIF2AK3PDE5A | |
| SCHEMBL31728133 | 0.74 | CLK1 (0.36) | CLK1EPHB4EIF2AK3 | |
| SCHEMBL31728018 | 0.74 | CLK1 (0.36) | CLK1EPHB4EIF2AK3 | |
| SCHEMBL31727792 | 0.73 | PDCD1LG2 (0.36) | CLK1EPHB4EIF2AK3PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |