Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 12/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.36 |
| ▸ | ABL1 | P00519 | 10/20 | 0.36 |
| ▸ | EGFR | P00533 | 10/20 | 0.36 |
| ▸ | HCK | P08631 | 10/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.36 |
| ▸ | MTOR | P42345 | 10/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 10/20 | 0.36 |
| ▸ | PRKDC | P78527 | 10/20 | 0.36 |
| ▸ | KDR | P35968 | 9/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 8/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31728341 | 0.92 | SRC (0.34) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31727755 | 0.85 | SRC (0.34) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31729198 | 0.85 | — | — | |
| SCHEMBL31728890 | 0.82 | SRC (0.38) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31728790 | 0.82 | SRC (0.38) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31729266 | 0.82 | SRC (0.36) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31728128 | 0.82 | SRC (0.35) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31728464 | 0.82 | SRC (0.38) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31729162 | 0.82 | SRC (0.36) | SRCPIK3CDABL1EGFRHCK | |
| SCHEMBL31728401 | 0.81 | SRC (0.39) | SRCPIK3CDABL1EGFRHCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |