Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 14/20 | 0.32 |
| ▸ | ABL1 | P00519 | 11/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.32 |
| ▸ | EGFR | P00533 | 10/20 | 0.32 |
| ▸ | HCK | P08631 | 10/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.32 |
| ▸ | MTOR | P42345 | 10/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 10/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 10/20 | 0.32 |
| ▸ | PRKDC | P78527 | 10/20 | 0.32 |
| ▸ | KDR | P35968 | 9/20 | 0.32 |
| ▸ | PI4KB | Q9UBF8 | 9/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31727748 | 0.88 | ABL1 (0.31) | SRCABL1EGFRHCKPIK3CB | |
| SCHEMBL31728531 | 0.81 | — | — | |
| SCHEMBL31727943 | 0.81 | PIK3CD (0.35) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL31728767 | 0.80 | PIK3CD (0.41) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL31727967 | 0.80 | SRC (0.36) | SRCABL1EGFRKDR | |
| SCHEMBL31728369 | 0.75 | KDR (0.34) | SRCEGFREPHB4KDR | |
| SCHEMBL31727802 | 0.73 | SRC (0.34) | SRCABL1PIK3CDEGFRHCK | |
| SCHEMBL31728790 | 0.72 | SRC (0.38) | PDE5ASRCABL1PIK3CDEGFR | |
| SCHEMBL31728890 | 0.72 | SRC (0.38) | PDE5ASRCABL1PIK3CDEGFR | |
| SCHEMBL31728048 | 0.68 | PDE5A (0.44) | PDE5ASRCABL1PIK3CDEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235874-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |