Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 11/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 11/20 | 0.54 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PRKCG | P05129 | 1/20 | 0.42 |
| ▸ | PRKCB | P05771 | 1/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | PRKCH | P24723 | 1/20 | 0.42 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.42 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520618 | 0.86 | DDB1 (0.52) | DDB1CRBNSCN9AKDM4EMAPT | |
| SCHEMBL31451208 | 0.86 | DDB1 (0.54) | DDB1CRBNSCN9AMAPTPRKCG | |
| SCHEMBL31620092 | 0.85 | DDB1 (0.49) | DDB1CRBNSCN9AKDM4EMAPT | |
| SCHEMBL31729374 | 0.84 | DDB1 (0.43) | DDB1CRBN | |
| SCHEMBL23540247 | 0.83 | DDB1 (0.75) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL30026749 | 0.83 | DDB1 (0.75) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL24319591 | 0.83 | DDB1 (0.58) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL31729305 | 0.82 | DDB1 (0.54) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL23301622 | 0.82 | CRBN (0.67) | DDB1CRBNKDM4EMAPTTHRB | |
| SCHEMBL25187964 | 0.82 | CRBN (0.67) | DDB1CRBNKDM4EMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235298-A1 | BIFUNCTIONAL COMPOUNDS CONTAINING THIAZOLYL DERIVATIVES FOR DEGRADING CERTAIN CYCLIN-DEPENDENT KINASE VIA UBIQUITIN PROTEASOME PATHWAY | NIKANG THERAPEUTICS, INC. (US) | 2025-11-13 | — | — | WO | disclosed |