Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.45 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12651278 | 0.76 | AXL (0.46) | AXLMKNK1MKNK2L3MBTL1MAPT | |
| SCHEMBL16256222 | 0.73 | AXL (0.53) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL4419544 | 0.73 | AXL (0.53) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL12609120 | 0.72 | STK17B (0.47) | POLBAXLMKNK1MKNK2ALDH1A1 | |
| SCHEMBL15881921 | 0.71 | HTT (0.59) | MEN1KMT2AGAASMN1; SMN2L3MBTL1 | |
| SCHEMBL12125652 | 0.69 | AXL (0.49) | MEN1KMT2AGAAAXLMKNK1 | |
| SCHEMBL31729077 | 0.67 | AXL (0.42) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL4572141 | 0.66 | AXL (0.53) | MEN1KMT2AAXLMKNK1MKNK2 | |
| SCHEMBL10965684 | 0.66 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL10965679 | 0.66 | SMN1; SMN2 (0.40) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025235872-A1 | HETEROCYCLICS AS EGFR INHIBITORS | SCHRÖDINGER, INC. (US) | 2025-11-13 | — | — | WO | disclosed |