SCHEMBL31730164

SCHEMBL31730164

O=C1CCCC(n2nc(Cl)ccc2=O)C(=O)N1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 19/20 0.42
▸ DDB1 Q16531 16/20 0.42
▸ IKZF3 Q9UKT9 3/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ CHRM2 P08172 1/20 0.38
▸ OPRM1 P35372 1/20 0.38
▸ CYP1A2 P05177 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29347228 0.79 CRBN (0.48) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL19586204 0.74 CRBN (0.49) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31730213 0.74 CRBN (0.46) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31730090 0.70 CRBN (0.53) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL19586591 0.70 CRBN (0.53) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL19586647 0.69 CRBN (0.44) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL29346196 0.69 CRBN (0.46) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31730099 0.68 CRBN (0.51) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL29347524 0.68 CRBN (0.52) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL29346446 0.67 CRBN (0.45) CRBNDDB1IKZF3ALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 — — EP disclosed
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