Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | CLK1 | P49759 | 5/20 | 0.37 |
| ▸ | CLK2 | P49760 | 5/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.37 |
| ▸ | HIPK1 | Q86Z02 | 4/20 | 0.37 |
| ▸ | HIPK2 | Q9H2X6 | 4/20 | 0.37 |
| ▸ | HIPK3 | Q9H422 | 4/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 4/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30896434 | 0.80 | ACVR1 (0.43) | ACVR1IDO1CLK1CLK2DYRK1A | |
| SCHEMBL27194961 | 0.80 | ACVR1 (0.43) | ACVR1IDO1CLK1CLK2DYRK1A | |
| SCHEMBL31730859 | 0.77 | ACVR1 (0.58) | ACVR1PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL31730763 | 0.77 | ACVR1 (0.56) | ACVR1NPC1MEN1KMT2ACLK1 | |
| SCHEMBL31730668 | 0.75 | TOP2A (0.44) | ACVR1NPC1RAB9AGRM4TGFBR1 | |
| SCHEMBL31730856 | 0.73 | COMT (0.53) | ACVR1NPC1CLK1CLK2DYRK1A | |
| SCHEMBL31730922 | 0.73 | ACVR1 (0.49) | ACVR1NPC1MEN1KMT2ACLK1 | |
| SCHEMBL31730774 | 0.73 | GRM5 (0.46) | ACVR1PDE4APDE4BPDE4DPDE4C | |
| SCHEMBL31730836 | 0.72 | ACVR1 (0.59) | ACVR1NPC1CLK1CLK2DYRK1A | |
| SCHEMBL6170227 | 0.72 | PIP4K2A (0.44) | PDE4APDE4BPDE4DPDE4CNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250352550-A1 | SUBSTITUTED FUROPYRIDINES FOR THERAPEUTIC USE | UNIV MASARYKOVA (CZ) | 2025-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250352550-A1 | SUBSTITUTED FUROPYRIDINES FOR THERAPEUTIC USE | FLT3, ROS1, MAP4K2 | ACVR1 1572/4885PDE4A 1025/4885PDE4B 1205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.