Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.65 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.65 |
| ▸ | EGFR | P00533 | 18/20 | 0.59 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | ROS1 | P08922 | 1/20 | 0.56 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.56 |
| ▸ | FLT4 | P35916 | 1/20 | 0.56 |
| ▸ | FLT3 | P36888 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.54 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553702 | 1.00 | MKNK1 (0.65) | MKNK1MKNK2EGFRJAK2ROS1 | |
| SCHEMBL30883869 | 0.92 | MKNK1 (0.68) | MKNK1MKNK2EGFRJAK2ROS1 | |
| SCHEMBL17822320 | 0.92 | MKNK1 (0.68) | MKNK1MKNK2EGFRJAK2ROS1 | |
| SCHEMBL28349264 | 0.90 | MKNK1 (0.60) | MKNK1MKNK2EGFRJAK2ROS1 | |
| SCHEMBL14660723 | 0.90 | MKNK2 (0.68) | MKNK1MKNK2EGFRJAK2ROS1 | |
| SCHEMBL14660648 | 0.90 | MKNK1 (0.65) | MKNK1MKNK2EGFRJAK2ROS1 | |
| SCHEMBL32671769 | 0.90 | MKNK1 (0.65) | MKNK1MKNK2EGFRJAK2ROS1 | |
| SCHEMBL29555980 | 0.90 | MKNK1 (0.65) | MKNK1MKNK2EGFRJAK2ROS1 | |
| Hydrochloric Acid SCHEMBL31218386 | 0.89 | MKNK1 (0.64) | MKNK1MKNK2EGFRJAK2ROS1 | |
| SCHEMBL31544713 | 0.89 | MKNK1 (0.64) | MKNK1MKNK2EGFRIGF1RMLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025238661-A1 | AN IMPROVED PROCESS FOR THE PREPARATION OF OSIMERTINIB | BDR LIFESCIENCES PRIVATE LIMITED (IN) | 2025-11-20 | — | — | WO | disclosed |