Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 6/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173307 | 1.00 | ESR2 (0.51) | ESR2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL15912459 | 0.88 | SLC6A4 (0.51) | ESR2CYP2C9ESR1CYP3A4SLC6A4 | |
| SCHEMBL18704035 | 0.85 | CYP2C9 (0.49) | ESR2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL29587032 | 0.85 | CYP2C9 (0.49) | ESR2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL1119887 | 0.84 | ESR2 (0.71) | ESR2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL1531852 | 0.84 | ESR2 (0.71) | ESR2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL11141777 | 0.83 | CYP2C9 (0.49) | ESR2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL11141773 | 0.83 | CYP2C9 (0.49) | ESR2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL11145063 | 0.83 | CYP2C9 (0.49) | ESR2CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL11145000 | 0.83 | CYP2C9 (0.49) | ESR2CYP2C9ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1225162-B1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PROD & CHEM (US) | 2005-03-16 | — | — | EP | claimed |
| US-20030100806-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | LAL GAURI SANKAR (US) | 2003-05-29 | — | — | US | claimed |
| US-6515191-B2 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PRODUCTS AND CHEMICALS, INC. | 2003-02-04 | — | — | US | claimed |
| US-20020198417-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | VERSUM MATERIALS US, LLC | 2002-12-26 | — | — | US | claimed |
| US-20020099247-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | AIR PRODUCTS AND CHEMICALS, INC. | 2002-07-25 | — | — | US | claimed |
| EP-1225162-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-07-24 | — | — | EP | claimed |
| EP-1452514-B1 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK & CHEMICALS (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-1273562-B1 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK & CHEMICALS (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-7145047-B2 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2006-12-05 | — | — | US | disclosed |
| US-6894200-B2 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2005-05-17 | — | — | US | disclosed |
| EP-1225162-B1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PROD & CHEM (US) | 2005-03-16 | — | — | EP | disclosed |
| EP-0952135-B1 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK & CHEMICALS (JP) | 2005-01-05 | — | — | EP | disclosed |
| EP-1452514-A1 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-20020198417-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | VERSUM MATERIALS US, LLC | 2002-12-26 | — | — | US | disclosed |
| US-6468607-B1 | MISCIBILITY, LARGE BIREFRINGENCE INDEX, NO STRONGLY POLAR GROUP IN ITS MOLECULE AND THUS CAN ALSO BE USED FOR ACTIVE MATRIX DRIVING, WIDE TEMPERATURE RANGE AND REQUIRES A HIGH SPEED RESPONSE AND A LOW VOLTAGE DRIVING | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6455744-B1 | MIXING SOLUTION OF A TETRAFLUORO DERIVATIVE OF AN AROMATIC COMPOUND IN AN ORGANIC SOLVENT WITH REDUCING AGENT IN AQUEOUS AMMONIA, UNDER AN INERT GAS, TO FORM AN AROMATIC COMPOUND CONTAINING TWO VICINAL FLUORINE ATOMS | AIR PRODUCTS AND CHEMICALS, INC. | 2002-09-24 | — | — | US | disclosed |
| US-20020099247-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | AIR PRODUCTS AND CHEMICALS, INC. | 2002-07-25 | — | — | US | disclosed |
| EP-1225162-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-0952135-A1 | Naphthalene derivative and liquid crystal composition comprising the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-10-27 | — | — | EP | disclosed |
| US-4386007-A | ELECTROOPTIC DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030100806-A1 | Synthesis of vicinal difluoro aromatics and intermediates thereof | PAH, AHR, HAAO | ESR2 1276/4885CYP2C9 156/4885ALDH1A1 1149/4885 |
| US-20020099247-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | PAH, AHR, HAAO | ESR2 1276/4885CYP2C9 156/4885ALDH1A1 1149/4885 |
| US-20020198417-A1 | SYNTHESIS OF VICINAL DIFLUORO AROMATICS AND INTERMEDIATES THEREOF | PAH, AHR, HAAO | ESR2 1276/4885CYP2C9 156/4885ALDH1A1 1149/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.