Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 5/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31733624 | 1.00 | CYP2D6 (0.41) | CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31733727 | 0.91 | CYP2D6 (0.44) | CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31733631 | 0.91 | CYP2D6 (0.44) | CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31733555 | 0.91 | CYP2D6 (0.44) | CYP2D6CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL31733611 | 0.84 | TYR (0.40) | CYP2D6CYP3A4HTR2ASLC6A4KCNH2 | |
| SCHEMBL31733294 | 0.84 | TYR (0.40) | CYP2D6CYP3A4HTR2ASLC6A4KCNH2 | |
| SCHEMBL20237734 | 0.83 | CYP2D6 (0.44) | CYP2D6HTR2ASLC6A4KCNH2SCN1A | |
| SCHEMBL29668705 | 0.83 | CYP2D6 (0.44) | CYP2D6HTR2ASLC6A4KCNH2SCN1A | |
| SCHEMBL20237736 | 0.83 | CYP2D6 (0.44) | CYP2D6HTR2ASLC6A4KCNH2SCN1A | |
| SCHEMBL20237732 | 0.83 | CYP2D6 (0.44) | CYP2D6HTR2ASLC6A4KCNH2SCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025237891-A1 | QUINOLINE-2-CARBOXAMIDE DERIVATIVES AS RAD51 INHIBITORS FOR THE TREATMENT OF CANCER | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2025-11-20 | — | — | WO | disclosed |