Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18800228 | 1.00 | CYP3A4 (0.46) | CYP3A4CYP2D6KDM4ESMN1; SMN2HTT | |
| SCHEMBL26287093 | 0.98 | CYP3A4 (0.47) | CYP3A4CYP2D6KDM4ESMN1; SMN2PARP1 | |
| SCHEMBL12443460 | 0.98 | CYP3A4 (0.47) | CYP3A4CYP2D6KDM4ESMN1; SMN2PARP1 | |
| SCHEMBL9921656 | 0.98 | CYP3A4 (0.47) | CYP3A4CYP2D6KDM4ESMN1; SMN2PARP1 | |
| SCHEMBL490080 | 0.92 | CYP3A4 (0.53) | CYP3A4CYP2D6KDM4ESMN1; SMN2HTT | |
| SCHEMBL172515 | 0.92 | CYP3A4 (0.53) | CYP3A4CYP2D6KDM4ESMN1; SMN2HTT | |
| SCHEMBL9020148 | 0.92 | CYP3A4 (0.53) | CYP3A4CYP2D6KDM4ESMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL490045 | 0.90 | CYP3A4 (0.51) | CYP3A4CYP2D6KDM4ESMN1; SMN2HTT | |
| SCHEMBL15374826 | 0.84 | — | — | |
| SCHEMBL29865289 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4653438-A1 | MACROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR, AND USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2025-11-26 | — | — | EP | disclosed |