Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23120392 | 0.85 | NR1H2 (0.46) | NR1H2EPHX1HPGDMEN1ALDH1A1 | |
| SCHEMBL23121128 | 0.85 | NR1H2 (0.46) | NR1H2EPHX1HPGDMEN1ALDH1A1 | |
| SCHEMBL31735215 | 0.84 | NR1H2 (0.50) | NR1H2EPHX1HPGDMEN1ALDH1A1 | |
| SCHEMBL24501246 | 0.84 | HPGD (0.49) | NR1H2EPHX1HPGDMEN1ALDH1A1 | |
| SCHEMBL18921586 | 0.84 | NR1H2 (0.54) | NR1H2EPHX1HPGDMEN1ALDH1A1 | |
| SCHEMBL3912059 | 0.84 | NR1H2 (0.54) | NR1H2EPHX1HPGDMEN1ALDH1A1 | |
| SCHEMBL3912061 | 0.84 | NR1H2 (0.54) | NR1H2EPHX1HPGDMEN1ALDH1A1 | |
| SCHEMBL18901865 | 0.81 | NR1H2 (0.53) | NR1H2EPHX1HPGDMEN1ALDH1A1 | |
| SCHEMBL30750600 | 0.81 | NR1H2 (0.53) | NR1H2HPGDMEN1ALDH1A1MAPT | |
| SCHEMBL28794123 | 0.81 | NR1H2 (0.53) | NR1H2EPHX1HPGDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025245351-A1 | SUBSTITUTED ARYL SULFONAMIDES AND COMPOSITIONS AND USES THEREOF | XENON PHARMACEUTICALS INC. (CA) | 2025-11-27 | — | — | WO | disclosed |