SCHEMBL31735629

SCHEMBL31735629

Cc1noc(C)c1-c1cc(-c2ccccc2O)c2ccn(C)c2c1

nearest known ligand 0.44

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 14/20 0.44
▸ BRD2 P25440 1/20 0.43
▸ CREBBP Q92793 2/20 0.41
▸ HSD11B1 P28845 2/20 0.40
▸ ERN1 O75460 2/20 0.39
▸ FTO Q9C0B1 1/20 0.39
▸ LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735489 0.88 BRD4 (0.45) BRD4BRD2CREBBPHSD11B1FTO
SCHEMBL31735502 0.84 BRD4 (0.42) BRD4BRD2CREBBPLMNA
SCHEMBL31735381 0.77 BRD4 (0.44) BRD4BRD2CREBBPFTO
SCHEMBL31735787 0.77 BRD4 (0.37) BRD4BRD2CREBBPFTO
SCHEMBL31735538 0.76 BRD4 (0.52) BRD4BRD2CREBBP
SCHEMBL31735877 0.73 BRD4 (0.51) BRD4BRD2CREBBPERN1FTO
SCHEMBL16429065 0.72 BRD4 (0.56) BRD4BRD2CREBBPERN1
SCHEMBL31735803 0.72 BRD4 (0.44) BRD4BRD2CREBBPLMNA
Hydrochloric Acid SCHEMBL23174958 0.71 BRD4 (0.55) BRD4BRD2CREBBPERN1
SCHEMBL31735505 0.71 BRD4 (0.47) BRD4BRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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