SCHEMBL31735644

SCHEMBL31735644

CC(=O)N1CCC(n2ccc3c(Cl)c(Nc4cnn(C)c(=O)c4C)ccc32)C1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 3/20 0.37
▸ BRD9 Q9H8M2 3/20 0.37
▸ KAT2B Q92831 13/20 0.36
▸ KDM1A O60341 1/20 0.36
▸ LRRK2 Q5S007 1/20 0.36
▸ BPTF Q12830 2/20 0.36
▸ IGF1R P08069 2/20 0.35
▸ CDK2 P24941 2/20 0.35
▸ KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735915 0.93 BRD9 (0.38) BRD4BRD9KAT2BKDM1ALRRK2
SCHEMBL31735484 0.90 LRRK2 (0.37) BRD4BRD9KAT2BKDM1ALRRK2
SCHEMBL31735916 0.85 BRD9 (0.37) BRD4BRD9KDM1AIGF1RCDK2
SCHEMBL31735773 0.82 BRD4 (0.39) BRD4BRD9KAT2BBPTFIGF1R
SCHEMBL31735682 0.82 BRD4 (0.39) BRD4BRD9KAT2BBPTFIGF1R
SCHEMBL31735728 0.82 BRD4 (0.39) BRD4BRD9KAT2BBPTFIGF1R
SCHEMBL31735437 0.78 BPTF (0.46) BRD4BRD9KAT2BBPTF
SCHEMBL31735652 0.77 BRD4 (0.40) BRD4BRD9KAT2BLRRK2BPTF
SCHEMBL31735454 0.75 BRD4 (0.45) BRD4BRD9KAT2BBPTF
SCHEMBL31735453 0.74 KDM1A (0.38) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 — — WO disclosed
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