SCHEMBL31735804

SCHEMBL31735804

Cc1c(Nc2ccc3c(ccn3C)c2)cnn(C)c1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 6/20 0.45
BRD9 Q9H8M2 5/20 0.45
KAT2B Q92831 2/20 0.45
GRM4 Q14833 1/20 0.43
BPTF Q12830 8/20 0.43
MEN1 O00255 2/20 0.43
TP53 P04637 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP3A4 P08684 2/20 0.43
CYP2D6 P10635 2/20 0.43
MAPT P10636 2/20 0.43
CYP2C19 P33261 2/20 0.43
HTR2B P41595 2/20 0.43
RECQL P46063 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
HTR2C P28335 3/20 0.42
PKM P14618 2/20 0.42
EGFR P00533 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31735577 0.86 BPTF (0.60) BRD4BRD9KAT2BBPTFMEN1
SCHEMBL31735631 0.86 BRD4 (0.42) BRD4BRD9KAT2BBPTF
SCHEMBL31735408 0.84 BRD4 (0.43) BRD4BRD9KAT2BGRM4BPTF
SCHEMBL31735663 0.83 BPTF (0.42) BRD4BRD9KAT2BGRM4BPTF
SCHEMBL31735890 0.82 BRD4 (0.45) BRD4BRD9KAT2BBPTFHTR2B
SCHEMBL31735476 0.82 BRD4 (0.40) BRD4BRD9KAT2BBPTF
SCHEMBL31735425 0.82 BRD4 (0.41) BRD4BRD9KAT2BBPTFEGFR
SCHEMBL31735471 0.81 BPTF (0.40) BRD4BRD9KAT2BBPTF
SCHEMBL31735878 0.81 BRD4 (0.42) BRD4BRD9KAT2BBPTF
SCHEMBL31735618 0.80 MAOB (0.44) BRD4BRD9KAT2BGRM4BPTF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245484-A1 FOXN1 ACTIVATORS THYMOFOX INC. (US) 2025-11-27 WO disclosed