Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 18/20 | 0.47 |
| ▸ | EIF2S1 | P05198 | 17/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31736263 | 1.00 | EIF2AK3 (0.47) | EIF2AK3EIF2S1CSF1R | |
| SCHEMBL31736133 | 0.96 | EIF2AK3 (0.43) | EIF2AK3EIF2S1CSF1R | |
| SCHEMBL31736331 | 0.96 | EIF2AK3 (0.43) | EIF2AK3EIF2S1CSF1R | |
| SCHEMBL31736261 | 0.94 | EIF2AK3 (0.42) | EIF2AK3EIF2S1 | |
| SCHEMBL31735999 | 0.94 | EIF2AK3 (0.42) | EIF2AK3EIF2S1 | |
| SCHEMBL31736156 | 0.93 | EIF2AK3 (0.52) | EIF2AK3EIF2S1 | |
| SCHEMBL31736185 | 0.93 | EIF2AK3 (0.52) | EIF2AK3EIF2S1 | |
| SCHEMBL31736288 | 0.93 | PSEN1 (0.42) | EIF2AK3EIF2S1 | |
| SCHEMBL31736191 | 0.93 | PSEN1 (0.42) | EIF2AK3EIF2S1 | |
| SCHEMBL31736167 | 0.92 | EIF2AK3 (0.41) | EIF2AK3EIF2S1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242872-A1 | 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Apollo AP45 Limited (GB) | 2025-11-27 | — | — | WO | claimed |
| WO-2025242872-A1 | 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Apollo AP45 Limited (GB) | 2025-11-27 | — | — | WO | disclosed |