Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 8/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | EIF2S1 | P05198 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31736172 | 1.00 | EGFR (0.38) | EGFRERBB2CSF1RMAPK14POLB | |
| SCHEMBL31736631 | 0.92 | EIF2AK3 (0.39) | EGFRERBB2CSF1REIF2AK3EIF2S1 | |
| SCHEMBL31736378 | 0.92 | EIF2AK3 (0.39) | EGFRERBB2CSF1REIF2AK3EIF2S1 | |
| SCHEMBL31736677 | 0.92 | EGFR (0.41) | EGFRERBB2CSF1REIF2AK3KDR | |
| SCHEMBL31736226 | 0.92 | EGFR (0.41) | EGFRERBB2CSF1REIF2AK3KDR | |
| SCHEMBL31736661 | 0.90 | CSF1R (0.42) | CSF1RMAPK14RIPK1KDRKIT | |
| SCHEMBL31736145 | 0.90 | CSF1R (0.42) | CSF1RMAPK14RIPK1KDRKIT | |
| SCHEMBL31736188 | 0.90 | CSF1R (0.43) | EGFRERBB2CSF1REIF2AK3KDR | |
| SCHEMBL31736142 | 0.90 | CSF1R (0.43) | EGFRERBB2CSF1REIF2AK3KDR | |
| SCHEMBL31736765 | 0.88 | KCNQ2 (0.36) | RIPK1EIF2AK3KDRKITEIF2S1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242872-A1 | 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Apollo AP45 Limited (GB) | 2025-11-27 | — | — | WO | disclosed |