Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29921991 | 0.88 | CA12 (0.53) | CA12CA1CA9KDM4ECYP17A1 | |
| SCHEMBL29071529 | 0.88 | CA12 (0.53) | CA12CA1CA9KDM4ECYP17A1 | |
| SCHEMBL4314672 | 0.88 | CA12 (0.49) | CA12CA1CA9CYP17A1ALDH1A1 | |
| SCHEMBL3784653 | 0.85 | CA12 (0.47) | CA12CA1CA9CYP17A1ALDH1A1 | |
| SCHEMBL15331757 | 0.84 | CA12 (0.49) | CA12CA1CA9KDM4ECYP17A1 | |
| SCHEMBL13197992 | 0.84 | CA12 (0.58) | CA12CA1CA9KDM4ECYP17A1 | |
| SCHEMBL25340465 | 0.84 | CA12 (0.46) | CA12CA1CA9CYP17A1ALDH1A1 | |
| SCHEMBL29535531 | 0.84 | CA12 (0.46) | CA12CA1CA9CYP17A1ALDH1A1 | |
| SCHEMBL15689378 | 0.84 | CA12 (0.46) | CA12CA1CA9CYP17A1ALDH1A1 | |
| SCHEMBL3781384 | 0.82 | CA12 (0.47) | CA12CA1CA9CYP17A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025242872-A1 | 1H-PYRAZOLO[4,3-D]PYRIMIDINE DERIVATIVES | Apollo AP45 Limited (GB) | 2025-11-27 | — | — | WO | disclosed |