SCHEMBL31737546

SCHEMBL31737546

NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CN)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ SLC15A2 Q16348 1/20 0.41
▸ QRFPR Q96P65 3/20 0.36
▸ F2 P00734 4/20 0.35
▸ APLNR P35414 2/20 0.34
▸ GRPR P30550 3/20 0.33
▸ MME P08473 1/20 0.33
▸ ECE1 P42892 1/20 0.33
▸ GLP1R P43220 1/20 0.32
▸ SCTR P47872 1/20 0.32
▸ BMP1 P13497 1/20 0.32
▸ MAGI3 Q5TCQ9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29271691 0.91 SLC15A2 (0.48) SLC15A2F2GRPRMMEECE1
SCHEMBL29435919 0.88 SLC15A2 (0.46) SLC15A2QRFPRMME
SCHEMBL29451161 0.88 SLC15A2 (0.46) SLC15A2QRFPRMME
SCHEMBL29888249 0.87 SLC15A2 (0.44) SLC15A2QRFPRMME
SCHEMBL29591824 0.86 SLC15A2 (0.42) SLC15A2QRFPRF2MMEECE1
SCHEMBL7807950 0.84 SLC15A2 (0.49) SLC15A2MMEECE1
SCHEMBL20783813 0.84 SLC15A2 (0.49) SLC15A2MME
SCHEMBL29590566 0.84 SLC15A2 (0.49) SLC15A2MME
SCHEMBL31453803 0.84 SLC15A2 (0.49) SLC15A2MME
SCHEMBL29630656 0.83 DPP4 (0.35) SLC15A2F2MMEECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025245292-A1 NON-NATURALLY OCCURRING MELANOCORTIN RECEPTOR AGONISTS AND USES THEREOF FOR MODULATING WEIGHT LOSS ENDEVICA BIO, INC. (US) 2025-11-27 — — WO disclosed
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