Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 8/20 | 1.00 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347746 | 0.81 | SOS1 (0.78) | SOS1TDP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4347750 | 0.81 | SOS1 (0.78) | SOS1TDP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL17762591 | 0.79 | SOS1 (0.69) | SOS1ALDH1A1 | |
| SCHEMBL4914275 | 0.79 | SOS1 (0.66) | SOS1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4347026 | 0.79 | SOS1 (0.66) | SOS1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17762644 | 0.78 | SOS1 (0.64) | SOS1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17762592 | 0.73 | SOS1 (0.58) | SOS1TDP1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL19498888 | 0.70 | MEN1 (0.68) | TDP1ALDH1A1 | |
| SCHEMBL6785097 | 0.69 | SOS1 (0.63) | SOS1DUSP22AMY1APTPN1DPP4 | |
| SCHEMBL6785099 | 0.69 | SOS1 (0.63) | SOS1DUSP22AMY1APTPN1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4659812-A1 | DETECTION METHODS AND COMBINATION THERAPIES OF CELLS WITH EXTRACELLULAR RAS EXPRESSION | Bumm, Thomas (DE) | 2025-12-10 | — | — | EP | disclosed |