Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.74 |
| ▸ | PLG | P00747 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17065041 | 1.00 | KLKB1 (0.74) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL25179508 | 0.97 | KLKB1 (0.69) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL29825447 | 0.94 | KLKB1 (0.73) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL17064326 | 0.94 | KLKB1 (0.73) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL31067499 | 0.91 | KLKB1 (0.68) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL17064988 | 0.91 | KLKB1 (0.68) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL25186440 | 0.90 | KLKB1 (0.60) | KLKB1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL17064603 | 0.88 | KLKB1 (0.72) | KLKB1 | |
| SCHEMBL29825676 | 0.88 | KLKB1 (0.72) | KLKB1 | |
| SCHEMBL29825430 | 0.88 | KLKB1 (0.72) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4663636-A2 | TRIFLUOROMETHYL SUBSTITUTED PYRAZOLES AS HUMAN PLASMA KALLIKREIN INHIBITORS | BioCryst Pharmaceuticals, Inc. (US) | 2025-12-17 | — | — | EP | disclosed |