Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.51 |
| ▸ | XIAP | P98170 | 1/20 | 0.51 |
| ▸ | MLYCD | O95822 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | CIT | O14578 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CASP6 | P55212 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15623783 | 0.79 | XIAP (0.68) | LTA4HTAAR1XIAPMEN1KMT2A | |
| SCHEMBL16981649 | 0.78 | HTT (0.66) | LTA4HTAAR1XIAPMEN1KMT2A | |
| SCHEMBL3167613 | 0.76 | TAAR1 (0.66) | LTA4HTAAR1XIAPMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11587657 | 0.75 | EPHX2 (0.58) | TAAR1MEN1KMT2AHTTEPHX2 | |
| SCHEMBL8274716 | 0.74 | TAAR1 (0.64) | LTA4HTAAR1XIAPMEN1KMT2A | |
| SCHEMBL15680102 | 0.74 | XIAP (0.62) | LTA4HTAAR1XIAPMEN1KMT2A | |
| SCHEMBL16888002 | 0.74 | XIAP (0.62) | LTA4HTAAR1XIAPMEN1KMT2A | |
| SCHEMBL11642853 | 0.74 | XIAP (0.70) | LTA4HTAAR1XIAPHTTALDH1A1 | |
| SCHEMBL11665786 | 0.74 | XIAP (0.62) | LTA4HTAAR1XIAPMEN1KMT2A | |
| SCHEMBL11645678 | 0.74 | XIAP (0.62) | LTA4HTAAR1XIAPMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645792-B2 | Prodrugs of propofol, compositions and uses thereof | XENOPORT, INC. (US) | 2010-01-12 | — | — | US | disclosed |
| US-7241807-B2 | Prodrugs of propofol, compositions and uses thereof | XENOPORT, INC. (US) | 2007-07-10 | — | — | US | disclosed |
| US-20060041011-A1 | Prodrugs of propofol, compositions and uses thereof | XENOPORT, INC. | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060041011-A1 | Prodrugs of propofol, compositions and uses thereof | CYP2C19, CYP3A5, CYP3A4 | LTA4H 1125/4885TAAR1 2765/4885XIAP 3936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.