SCHEMBL3174561

SCHEMBL3174561

COn1cc[nH]c1=S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methimazole SCHEMBL11566411 0.65
Methimazole SCHEMBL30524404 0.62
SCHEMBL11565383 0.62
SCHEMBL10025204 0.62
SCHEMBL2862280 0.62
SCHEMBL20558660 0.57
SCHEMBL11565100 0.55
SCHEMBL12172388 0.40
SCHEMBL192237 0.36
Benzene SCHEMBL527921 0.33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100010049-A1 Novel Tyrosinase inhibitors and pharmaceutical/cosmetic applications thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2010-01-14 US claimed
US-10287419-B2 Rubber composition and vulcanization aid SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-05-14 US disclosed
US-20170130028-A1 RUBBER COMPOSITION AND VULCANIZATION AID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-11 US disclosed
US-20170130028-A1 RUBBER COMPOSITION AND VULCANIZATION AID SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-11 US disclosed
EP-3075777-A1 RUBBER COMPOSITION AND VULCANIZATION AID Sumitomo Chemical Company Limited (JP) 2016-10-05 EP disclosed
US-20100010049-A1 Novel Tyrosinase inhibitors and pharmaceutical/cosmetic applications thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2010-01-14 US disclosed
US-20100010049-A1 Novel Tyrosinase inhibitors and pharmaceutical/cosmetic applications thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2010-01-14 US disclosed
US-20100010049-A1 Novel Tyrosinase inhibitors and pharmaceutical/cosmetic applications thereof GALDERMA RESEARCH & DEVELOPMENT (FR) 2010-01-14 US disclosed