SCHEMBL3174586

SCHEMBL3174586

CCCCCCCCOc1ccc(-n2nc3ccc(C)cc3n2)c(O)c1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.46
NPC1 O15118 1/20 0.42
LMNA P02545 1/20 0.42
RAB9A P51151 1/20 0.42
LTA4H P09960 1/20 0.41
CNR2 P34972 5/20 0.41
KDM4E B2RXH2 1/20 0.41
PLK1 P53350 3/20 0.40
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3171025 1.00 NR5A1 (0.46) NR5A1NPC1LMNARAB9ALTA4H
SCHEMBL3170837 1.00 NR5A1 (0.46) NR5A1NPC1LMNARAB9ALTA4H
SCHEMBL13370146 0.93 NR5A1 (0.50) NR5A1LTA4HCNR2
SCHEMBL3176314 0.89 NR5A1 (0.47) NR5A1NPC1RAB9ALTA4HCNR2
SCHEMBL3174626 0.88 NR5A1 (0.46) NR5A1NPC1RAB9ALTA4HCNR2
SCHEMBL13370102 0.88 NR5A1 (0.50) NR5A1NPC1LMNARAB9ALTA4H
SCHEMBL45837 0.88 NR5A1 (0.50) NR5A1NPC1LMNARAB9ALTA4H
SCHEMBL9744615 0.88 NR5A1 (0.50) NR5A1NPC1LMNARAB9ALTA4H
SCHEMBL5445426 0.88 NR5A1 (0.50) NR5A1NPC1LMNARAB9ALTA4H
SCHEMBL7787935 0.87 NR5A1 (0.45) NR5A1LTA4HCNR2THRATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8398235-B2 Plastic lens for spectacles, process for producing the same, and coating liquid applicator for use in the process HOYA CORPORATION (JP) 2013-03-19 US disclosed
US-20100014048-A1 PLASTIC LENS FOR SPECTACLES, PROCESS FOR PRODUCING THE SAME, AND COATING LIQUID APPLICATOR FOR USE IN THE PROCESS HOYA CORPORATION (JP) 2010-01-21 US disclosed
EP-2093605-A1 PLASTIC LENS FOR SPECTACLES, PROCESS FOR PRODUCING THE SAME, AND COATING LIQUID APPLICATOR FOR USE IN THE PROCESS HOYA CORPORATION (JP) 2009-08-26 EP disclosed