SCHEMBL31746948

SCHEMBL31746948

Cc1nc2[nH]ncc2cc1Nc1cccc2ccn(CC(=O)NCC(F)(F)F)c(=O)c12

nearest known ligand 0.42

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 19/20 0.42
KDM4E B2RXH2 1/20 0.36
DDR2 Q16832 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25073838 1.00 DDR1 (0.42) DDR1KDM4EDDR2
SCHEMBL25073903 0.89 DDR1 (0.44) DDR1DDR2
SCHEMBL31746911 0.89 DDR1 (0.44) DDR1DDR2
SCHEMBL25073911 0.85 DDR1 (0.43) DDR1DDR2
SCHEMBL31746920 0.84 DDR1 (0.43) DDR1KDM4E
SCHEMBL25073872 0.84 DDR1 (0.43) DDR1KDM4E
SCHEMBL31746900 0.83 DDR1 (0.42) DDR1DDR2
SCHEMBL25073910 0.83 DDR1 (0.42) DDR1DDR2
SCHEMBL25073840 0.83 DDR1 (0.44) DDR1DDR2
SCHEMBL30279189 0.83 DDR1 (0.44) DDR1DDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4387963-B1 PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 REDX PHARMA LTD (GB) 2025-12-24 EP disclosed