Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25073855 | 1.00 | NOTUM (0.42) | NOTUMNLRP3NTSR1NTRK1ALDH1A1 | |
| SCHEMBL25073779 | 0.92 | KDM4E (0.47) | NOTUMNLRP3NTSR1ALDH1A1RAB9A | |
| SCHEMBL31746968 | 0.92 | KDM4E (0.47) | NOTUMNLRP3NTSR1ALDH1A1RAB9A | |
| SCHEMBL31746873 | 0.92 | NOTUM (0.42) | NOTUMNLRP3NTSR1ALDH1A1RAB9A | |
| SCHEMBL25073816 | 0.92 | NOTUM (0.42) | NOTUMNLRP3NTSR1ALDH1A1RAB9A | |
| SCHEMBL25073756 | 0.91 | NOTUM (0.46) | NOTUMNLRP3NTSR1ALDH1A1RAB9A | |
| SCHEMBL31746915 | 0.91 | NOTUM (0.46) | NOTUMNLRP3NTSR1ALDH1A1RAB9A | |
| SCHEMBL25073740 | 0.89 | NOTUM (0.42) | NOTUMNLRP3NTSR1ALDH1A1RAB9A | |
| SCHEMBL31746913 | 0.89 | NOTUM (0.42) | NOTUMNLRP3NTSR1ALDH1A1RAB9A | |
| SCHEMBL31162393 | 0.89 | NOTUM (0.42) | NOTUMNLRP3ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4387963-B1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA LTD (GB) | 2025-12-24 | — | — | EP | disclosed |