Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2553587 | 0.63 | CCR8 (0.33) | CCR8KMT2A | |
| Hydrochloric Acid SCHEMBL15092651 | 0.62 | KMT2A (0.35) | CCR8KMT2A | |
| SCHEMBL2321239 | 0.58 | IDO1 (0.39) | — | |
| SCHEMBL3829382 | 0.52 | CCR8 (0.38) | CCR8KMT2A | |
| SCHEMBL8144096 | 0.51 | — | — | |
| SCHEMBL21564019 | 0.50 | CCR8 (0.59) | CCR8KMT2A | |
| SCHEMBL19318056 | 0.49 | CCR8 (1.00) | CCR8KMT2A | |
| SCHEMBL31023340 | 0.49 | CCR8 (0.44) | CCR8KMT2A | |
| SCHEMBL30774416 | 0.49 | CCR8 (1.00) | CCR8KMT2A | |
| SCHEMBL12410495 | 0.49 | CCR8 (0.56) | CCR8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388543-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250388543-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN | SCN8A, SCN1B, SCN3A | CCR8 100/4885KMT2A 3307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.