Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 8/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 8/20 | 0.44 |
| ▸ | SI | P14410 | 8/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.34 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31749808 | 0.92 | MGAM (0.50) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749531 | 0.90 | MGAM (0.53) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749893 | 0.90 | MGAM (0.37) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749467 | 0.88 | MGAM (0.42) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749571 | 0.87 | TDP1 (0.39) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749637 | 0.86 | MGAM (0.50) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749540 | 0.84 | MGAM (0.33) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749631 | 0.83 | MGAM (0.45) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749889 | 0.81 | GAA (0.59) | MGAMAMY1AGAASIMGAM2 | |
| SCHEMBL31749809 | 0.81 | GAA (0.34) | MGAMAMY1AGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025264724-A1 | MPRO INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-12-26 | — | — | WO | disclosed |