SCHEMBL3175177

SCHEMBL3175177

O=C(Nc1ccccc1-c1ccccc1)OC1CCN(CCCCCCCCCNC(=O)c2ccc(F)c(F)c2O)CC1

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CHRM3 P20309 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1922602 0.91 CHRM3 (0.68) CHRM3
SCHEMBL1922419 0.90 CHRM3 (0.64) CHRM3
SCHEMBL1924455 0.90 CHRM3 (0.64) CHRM3
SCHEMBL1922949 0.90 CHRM3 (0.66) CHRM3
SCHEMBL3229187 0.89 CHRM3 (0.59) CHRM3
SCHEMBL1922817 0.89 CHRM3 (0.64) CHRM3
SCHEMBL1922575 0.87 CHRM3 (0.64) CHRM3
SCHEMBL1923277 0.86 CHRM3 (0.66) CHRM3
SCHEMBL1922591 0.86 CHRM3 (0.63) CHRM3
SCHEMBL1922141 0.86 CHRM3 (0.63) CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010007552-A1 NOVEL COMPOUNDS ACTIVE AS MUSCARINIC RECEPTOR ANTAGONISTS PFIZER LIMITED (GB) 2010-01-21 WO disclosed
US-20100016366-A1 Novel Compounds Active as Muscarinic Receptor Antagonists GLOSSOP PAUL ALAN 2010-01-21 US disclosed
US-20100016366-A1 Novel Compounds Active as Muscarinic Receptor Antagonists GLOSSOP PAUL ALAN 2010-01-21 US disclosed
US-20100016366-A1 Novel Compounds Active as Muscarinic Receptor Antagonists GLOSSOP PAUL ALAN 2010-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016366-A1 Novel Compounds Active as Muscarinic Receptor Antagonists CHRM3, CHRM2, CHRM5 CHRM3 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.