⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058947 | 0.92 | — | — | |
| SCHEMBL10990 | 0.92 | — | — | |
| SCHEMBL715867 | 0.92 | GSK3B (1.00) | — | |
| SCHEMBL33524954 | 0.92 | — | — | |
| SCHEMBL7021498 | 0.92 | — | — | |
| SCHEMBL1599522 | 0.92 | — | — | |
| SCHEMBL693917 | 0.92 | GSK3B (1.00) | — | |
| Hydroxyamine SCHEMBL27087760 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL4263587 | 0.88 | — | — | |
| Charcoal, Activated SCHEMBL8357494 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109265512-B | Preparation method of protein conjugate based on pyridine dicarbaldehyde | 清华大学 | 2021-06-11 | — | — | CN | disclosed |
| CN-109265512-A | The preparation method of protein conjugate based on pyridine dicarbaldehyde | 清华大学 | 2019-01-25 | — | — | CN | disclosed |
| CN-105267973-B | Cancer targeting peptides for enhancing anticancer drug delivery and therapeutic effects | 中央研究院 | 2019-01-08 | — | — | CN | disclosed |
| US-20170000859-A1 | NON-NATURAL RIBONUCLEASE CONJUGATES AS CYTOTOXIC AGENTS | QUINTESSENCE BIOSCIENCES | 2017-01-05 | — | — | US | disclosed |
| CN-106110311-A | Blood coagulation protein conjugates | 百深公司 | 2016-11-16 | — | — | CN | disclosed |
| US-9393319-B2 | Non-natural ribonuclease conjugates as cytotoxic agents | QUINTESSENCE BIOSCIENCES, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| CN-105267973-A | Cancer targeting peptides for enhancing anticancer drug delivery and therapeutic effects | ACADEMIA SINICA | 2016-01-27 | — | — | CN | disclosed |
| US-20140212946-A1 | NON-NATURAL RIBONUCLEASE CONJUGATES AS CYTOTOXIC AGENTS | QUINTESSENCE BIOSCIENCES, INC. (US) | 2014-07-31 | — | — | US | disclosed |
| US-8697065-B2 | Non-natural ribonuclease conjugates as cytotoxic agents | QUINTESSENCE BIOSCIENCES, INC. (US) | 2014-04-15 | — | — | US | disclosed |
| US-20140017241-A1 | NON-NATURAL RIBONUCLEASE CONJUGATES AS CYTOTOXIC AGENTS | QUINTESSENCE BIOSCIENCES, INC. (US) | 2014-01-16 | — | — | US | disclosed |
| US-8470315-B2 | Non-natural ribonuclease conjugates as cytotoxic agents | QUINTESSENCE BIOSCIENCES, INC. (US) | 2013-06-25 | — | — | US | disclosed |
| US-20100015068-A1 | Methods and Compositions For Altering Biological Surfaces | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-01-21 | — | — | US | disclosed |
| WO-2008005509-A2 | METHODS AND COMPOSITIONS FOR ALTERING BIOLOGICAL SURFACES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-01-10 | — | — | WO | disclosed |
| US-20070281036-A1 | System and method of delivering a desired material to a cell | UNIVERSITY OF VERMONT AND STATE AGRICULTURAL COLLEGE (US) | 2007-12-06 | — | — | US | disclosed |
| EP-1740220-A2 | NON-NATURAL RIBONUCLEASE CONJUGATES AS CYTOTOXIC AGENTS | Quintessence Biosciences, Inc. (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005115477-A2 | NON-NATURAL RIBONUCLEASE CONJUGATES AS CYTOTOXIC AGENTS | QUINTESSENCE BIOSCIENCES, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
| US-20050261232-A1 | Non-natural ribonuclease conjugates as cytotoxic agents | QUINTESSENCE BIOSCIENCES, INC. (US) | 2005-11-24 | — | — | US | disclosed |