Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15494738 | 0.88 | MAPK1 (0.53) | MAPK1CHRM2GRM5SIGMAR1KDM4E | |
| SCHEMBL2109394 | 0.84 | MAPK1 (0.51) | MAPK1CHRM2GRM5SIGMAR1KDM4E | |
| SCHEMBL15494739 | 0.84 | MAPK1 (0.51) | MAPK1CHRM2GRM5SIGMAR1KDM4E | |
| SCHEMBL31044611 | 0.80 | MAPK1 (0.57) | MAPK1CHRM2GRM5SIGMAR1KDM4E | |
| SCHEMBL16011728 | 0.80 | MAPK1 (0.57) | MAPK1CHRM2GRM5SIGMAR1KDM4E | |
| SCHEMBL155925 | 0.78 | MAPK1 (0.54) | MAPK1CHRM2GRM5SIGMAR1KDM4E | |
| SCHEMBL31044569 | 0.78 | MAPK1 (0.54) | MAPK1CHRM2GRM5SIGMAR1KDM4E | |
| SCHEMBL3458276 | 0.77 | PTPN11 (0.51) | — | |
| SCHEMBL16011559 | 0.77 | MAPK1 (0.50) | MAPK1CHRM2GRM5SIGMAR1KDM4E | |
| SCHEMBL4490117 | 0.77 | MAPK1 (0.53) | MAPK1CHRM2GRM5SIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025262297-A1 | PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 | DARK BLUE THERAPEUTICS LTD (GB) | 2025-12-26 | — | — | WO | disclosed |