Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 5/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696653 | 1.00 | SLC1A1 (0.56) | SLC1A1CTSSCTSKPPARGPPARA | |
| SCHEMBL8986524 | 1.00 | SLC1A1 (0.56) | SLC1A1CTSSCTSKPPARGPPARA | |
| SCHEMBL8986521 | 1.00 | SLC1A1 (0.56) | SLC1A1CTSSCTSKPPARGPPARA | |
| SCHEMBL10065844 | 1.00 | SLC1A1 (0.56) | SLC1A1CTSSCTSKPPARGPPARA | |
| SCHEMBL9463694 | 0.97 | SLC1A1 (0.54) | SLC1A1CTSSCTSKPPARGPPARA | |
| SCHEMBL24711924 | 0.88 | SLC1A1 (0.49) | SLC1A1CTSSCTSKPPARGPPARA | |
| SCHEMBL14942947 | 0.88 | SLC1A1 (0.49) | SLC1A1CTSSCTSKPPARGPPARA | |
| SCHEMBL12668877 | 0.88 | SLC1A1 (0.49) | SLC1A1CTSSCTSKPPARGPPARA | |
| SCHEMBL22290967 | 0.86 | SLC1A1 (0.57) | SLC1A1CTSSCTSKPPARGPPARA | |
| SCHEMBL30118360 | 0.85 | MME (0.50) | CTSSCTSKGPR34ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260001914-A1 | MACROCYCLIC PEPTIDES TARGETING KRAS | MERCK SHARP & DOHME LLC (US) | 2026-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260001914-A1 | MACROCYCLIC PEPTIDES TARGETING KRAS | KRAS, NRAS, HRAS | SLC1A1 2783/4885CTSS 1044/4885CTSK 1467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.