Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SCSF1RDRD2FLT1FLT3FLT4HTR1BHTR1DHTR1FKDRKITMETOPRD1OPRK1OPRM1PDGFRAPDGFRBRET
The experimentally established mechanism targets of Malic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 3/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TET2 | Q6N021 | 6/20 | 0.48 |
| ▸ | TET3 | O43151 | 2/20 | 0.48 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malic Acid SCHEMBL2711211 | 1.00 | CA4 (0.67) | CA4SMN1; SMN2TET2TET3TET1 | |
| Malic Acid SCHEMBL1577943 | 0.94 | CA4 (0.62) | CA4SMN1; SMN2TET2TET3TET1 | |
| Malic Acid SCHEMBL21569400 | 0.94 | CA4 (0.62) | CA4SMN1; SMN2TET2TET3TET1 | |
| Malic Acid SCHEMBL27637568 | 0.94 | CA4 (0.62) | CA4SMN1; SMN2TET2TET3TET1 | |
| Malic Acid SCHEMBL1813218 | 0.94 | CA4 (0.62) | CA4SMN1; SMN2TET2TET3TET1 | |
| Malic Acid SCHEMBL9243361 | 0.94 | CA4 (0.62) | CA4SMN1; SMN2TET2TET3TET1 | |
| Malic Acid SCHEMBL29365451 | 0.94 | CA4 (0.62) | CA4SMN1; SMN2TET2TET3TET1 | |
| Malic Acid SCHEMBL21569379 | 0.94 | CA4 (0.62) | CA4SMN1; SMN2TET2TET3TET1 | |
| Malic Acid SCHEMBL29511821 | 0.94 | CA4 (0.62) | CA4SMN1; SMN2TET2TET3TET1 | |
| Malic Acid SCHEMBL27658444 | 0.94 | CA4 (0.62) | CA4SMN1; SMN2TET2TET3TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4707350-A1 | TREATMENT LIQUID COMPOSITION FOR DYE PRINTING, INK SET, AND RECORDING METHOD | Seiko Epson Corporation (JP) | 2026-03-11 | — | — | EP | claimed |
| EP-4707350-A1 | TREATMENT LIQUID COMPOSITION FOR DYE PRINTING, INK SET, AND RECORDING METHOD | Seiko Epson Corporation (JP) | 2026-03-11 | — | — | EP | disclosed |
| CN-121270300-A | Multifunctional saline-alkali soil conditioner and preparation method thereof | 中盐安徽红四方肥业股份有限公司 | 2026-01-06 | — | — | CN | disclosed |