Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 20/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18018884 | 1.00 | LRRK2 (1.00) | LRRK2SLCO1B1 | |
| SCHEMBL16982511 | 0.92 | LRRK2 (1.00) | LRRK2SLCO1B1 | |
| SCHEMBL16982351 | 0.90 | LRRK2 (0.84) | LRRK2SLCO1B1 | |
| SCHEMBL18018881 | 0.89 | LRRK2 (1.00) | LRRK2SLCO1B1 | |
| SCHEMBL21738431 | 0.89 | LRRK2 (0.79) | LRRK2SLCO1B1 | |
| SCHEMBL16982465 | 0.87 | LRRK2 (0.91) | LRRK2SLCO1B1 | |
| SCHEMBL18018880 | 0.87 | LRRK2 (1.00) | LRRK2SLCO1B1 | |
| SCHEMBL18018916 | 0.87 | LRRK2 (1.00) | LRRK2SLCO1B1 | |
| SCHEMBL16982536 | 0.87 | LRRK2 (1.00) | LRRK2SLCO1B1 | |
| SCHEMBL18018893 | 0.86 | LRRK2 (1.00) | LRRK2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3778604-B1 | LRRK2 INHIBITORS AND METHODS OF MAKING AND USING THE SAME | DANA FARBER CANCER INST INC (US) | 2026-01-07 | — | — | EP | disclosed |