SCHEMBL31757797

SCHEMBL31757797

COC(=O)[C@H](CN1CCCC1)O[Si](C)(C)C(C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
NPSR1 Q6W5P4 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
PADI1 Q9ULC6 1/20 0.32
PADI4 Q9UM07 1/20 0.32
POLB P06746 1/20 0.32
CHRM2 P08172 2/20 0.32
ADRA2B P18089 2/20 0.32
DRD3 P35462 2/20 0.32
SIGMAR1 Q99720 2/20 0.32
HRH3 Q9Y5N1 2/20 0.32
ALDH1A1 P00352 5/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CYP2D6 P10635 1/20 0.31
ADRA2C P18825 1/20 0.31
CHRM3 P20309 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31757795 0.85 KMT2A (0.38) MEN1KMT2ANPSR1L3MBTL1POLB
SCHEMBL30377725 0.76 CA1 (0.32) SMN1; SMN2
SCHEMBL15369672 0.76 CA1 (0.39) SMN1; SMN2
SCHEMBL840025 0.74 CA1 (0.31)
SCHEMBL838763 0.74 CA1 (0.31)
SCHEMBL14237209 0.74 CA1 (0.31)
SCHEMBL3431904 0.74 CA1 (0.31)
SCHEMBL838764 0.74 CA1 (0.31)
SCHEMBL1526373 0.73 CA1 (0.33)
SCHEMBL1526372 0.73 CA1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP3, DPP7, DPP9 MEN1 3217/4885KMT2A 4083/4885NPSR1 1025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.