SCHEMBL31758043

SCHEMBL31758043

CCCCOCCn1c(=O)oc2ccc(-c3ccc(C[C@H](N)C#N)c(F)c3)cc21

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CTSC P53634 4/20 0.42
ASAH1 Q13510 1/20 0.40
CTSK P43235 1/20 0.39
ALDH1A1 P00352 3/20 0.38
TSHR P16473 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
MAPK1 P28482 1/20 0.37
HTT P42858 1/20 0.37
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RAB9A P51151 3/20 0.35
MEN1 O00255 1/20 0.34
NPC1 O15118 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31758753 0.88 CTSC (0.47) CTSCASAH1ALDH1A1
SCHEMBL31757778 0.84 CTSC (0.50) CTSCASAH1CTSK
SCHEMBL31757947 0.84 CTSC (0.50) CTSCASAH1CTSK
SCHEMBL31758042 0.83 CTSC (0.46) CTSCCTSK
SCHEMBL31757916 0.81 CTSC (0.42) CTSCCTSKL3MBTL1
SCHEMBL24981975 0.81 CTSC (0.56) CTSCCTSK
SCHEMBL31757811 0.81 CTSC (0.49) CTSCASAH1CTSK
SCHEMBL31757864 0.80 CTSC (0.49) CTSCCTSK
SCHEMBL31758046 0.80 CTSC (0.44) CTSCCTSKKMT2A
SCHEMBL31757955 0.79 CTSC (0.46) CTSCASAH1CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP9, DPP7, DPP4 CTSC 6/4885ASAH1 658/4885CTSK 770/4885
US-20260008758-A1 LINEAR DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP3, DPP7, DPP9 CTSC 6/4885ASAH1 807/4885CTSK 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.