SCHEMBL31758780

SCHEMBL31758780

CO[C@@H]1CCN(C(=O)OC(C)(C)C)C[C@@H](C(=O)N[C@H](C#N)Cc2ccc(-c3cc4c(C)nc(C)cn4c3)cc2F)OC1

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CTSC P53634 20/20 0.41
▸ CTSK P43235 12/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31758530 0.91 CTSC (0.41) CTSCCTSK
SCHEMBL31758833 0.91 CTSC (0.38) CTSC
SCHEMBL31758731 0.89 CTSC (0.41) CTSCCTSK
SCHEMBL31758876 0.89 CTSC (0.34) CTSC
SCHEMBL31758681 0.89 CTSC (0.39) CTSC
SCHEMBL31758551 0.89 CTSC (0.36) CTSCCTSK
SCHEMBL31702764 0.87 CTSC (0.55) CTSCCTSK
SCHEMBL31758548 0.86 CTSC (0.43) CTSCCTSK
SCHEMBL31758821 0.85 CTSC (0.45) CTSCCTSK
SCHEMBL31758811 0.81 CTSC (0.41) CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF INSMED INCORPORATED 2026-01-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260008760-A1 DIPEPTIDYL PEPTIDASE 1 INHIBITORS AND USES THEREOF DPP9, DPP7, DPP4 CTSC 6/4885CTSK 770/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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