Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 7/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.52 |
| ▸ | KMO | O15229 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL19664328 | 0.97 | SLC18A3 (0.58) | SLC18A3SIGMAR1CYP11B2CYP2D6KMO | |
| Benzene SCHEMBL11808437 | 0.97 | SLC18A3 (0.63) | SLC18A3SIGMAR1CYP11B2CYP2D6KMO | |
| SCHEMBL30731352 | 0.97 | SLC18A3 (0.63) | SLC18A3SIGMAR1CYP11B2CYP2D6KMO | |
| SCHEMBL11562787 | 0.97 | SLC18A3 (0.63) | SLC18A3SIGMAR1CYP11B2CYP2D6KMO | |
| SCHEMBL447032 | 0.97 | SLC18A3 (0.63) | SLC18A3SIGMAR1CYP11B2CYP2D6KMO | |
| SCHEMBL19262690 | 0.97 | SLC18A3 (0.63) | SLC18A3SIGMAR1CYP11B2CYP2D6KMO | |
| SCHEMBL790829 | 0.97 | SLC18A3 (0.63) | SLC18A3SIGMAR1CYP11B2CYP2D6KMO | |
| SCHEMBL19198566 | 0.97 | SLC18A3 (0.63) | SLC18A3SIGMAR1CYP11B2CYP2D6KMO | |
| SCHEMBL42833 | 0.97 | SLC18A3 (0.63) | SLC18A3SIGMAR1CYP11B2CYP2D6KMO | |
| SCHEMBL27995526 | 0.97 | SLC18A3 (0.63) | SLC18A3SIGMAR1CYP11B2CYP2D6KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655256-B2 | Mixture of ion exchange resin and drug | ROHM AND HAAS COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-20040126324-A1 | Pharmaceutical formulation including a resinate and an aversive agent | ROHM AND HAAS COMPANY | 2004-07-01 | — | — | US | disclosed |
| US-20030068276-A1 | Dosage forms | ROHM AND HAAS COMPANY | 2003-04-10 | — | — | US | disclosed |
| EP-1293195-A1 | Oral pharmaceutical dosage forms with reduced potential for drug abuse, comprising respiratory irritants or bitter substances | ROHM AND HAAS COMPANY (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0101198-B1 | BLOWING AGENT COMPOSITIONS AND THEIR USE IN EXPANDING RUBBERS AND PLASTICS | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1988-06-29 | — | — | EP | disclosed |
| US-4510097-A | Hindered aliphatic monoisocyanates | W. R. GRACE & CO. (US) | 1985-04-09 | — | — | US | disclosed |
| US-4482650-A | AZODICARBONAMIDE, ZINC COMPOUND, SULFINIC ACID DERIVATIVE | UNIROYAL, INC. (US) | 1984-11-13 | — | — | US | disclosed |
| US-4472536-A | PREMIXING AZODICARBONAMIDE, ZINC COMPOUND, AROMATIC SULFINIC ACID OR SALT | UNIROYAL, INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4444679-A | Blowing agent compositions | UNIROYAL, INC. (US) | 1984-04-24 | — | — | US | disclosed |
| EP-0101198-A2 | Blowing agent compositions and their use in expanding rubbers and plastics | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1984-02-22 | — | — | EP | disclosed |