Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178477 | 1.00 | EPHX2 (0.72) | EPHX2ALDH1A1FAAHRAB9ASMN1; SMN2 | |
| SCHEMBL3190084 | 0.92 | EPHX2 (0.68) | EPHX2ALDH1A1FAAHRAB9AEPHX1 | |
| SCHEMBL3190094 | 0.92 | EPHX2 (0.68) | EPHX2ALDH1A1FAAHRAB9AEPHX1 | |
| SCHEMBL3182145 | 0.90 | EPHX2 (0.74) | EPHX2ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3182153 | 0.90 | EPHX2 (0.74) | EPHX2ALDH1A1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL3192516 | 0.90 | EPHX2 (0.66) | EPHX2ALDH1A1FAAHRAB9AEPHX1 | |
| SCHEMBL3189594 | 0.90 | EPHX2 (0.66) | EPHX2ALDH1A1FAAHRAB9AEPHX1 | |
| SCHEMBL3189587 | 0.90 | EPHX2 (0.66) | EPHX2ALDH1A1FAAHRAB9AEPHX1 | |
| SCHEMBL3192506 | 0.90 | EPHX2 (0.66) | EPHX2ALDH1A1FAAHRAB9AEPHX1 | |
| SCHEMBL3183168 | 0.90 | EPHX2 (0.66) | EPHX2ALDH1A1FAAHRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | claimed |
| US-20160318856-A1 | Substituted Urea eIF2alpha Kinase Activators | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318856-A1 | Substituted Urea eIF2alpha Kinase Activators | EIF2AK1, EIF2A, EIF4A2 | EPHX2 3905/4885ALDH1A1 4322/4885FAAH 4078/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.