Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 19/20 | 0.97 |
| ▸ | FAAH | O00519 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3178573 | 1.00 | EPHX2 (0.97) | EPHX2FAAHNPC1RAB9A | |
| SCHEMBL3192513 | 0.99 | EPHX2 (1.00) | EPHX2FAAHNPC1RAB9A | |
| SCHEMBL3182099 | 0.99 | EPHX2 (1.00) | EPHX2FAAHNPC1RAB9A | |
| SCHEMBL3192505 | 0.99 | EPHX2 (1.00) | EPHX2FAAHNPC1RAB9A | |
| SCHEMBL3191149 | 0.99 | EPHX2 (1.00) | EPHX2FAAHNPC1RAB9A | |
| SCHEMBL3194212 | 0.99 | EPHX2 (1.00) | EPHX2FAAHNPC1RAB9A | |
| SCHEMBL3194206 | 0.99 | EPHX2 (1.00) | EPHX2FAAHNPC1RAB9A | |
| SCHEMBL3191141 | 0.99 | EPHX2 (1.00) | EPHX2FAAHNPC1RAB9A | |
| SCHEMBL3182106 | 0.99 | EPHX2 (1.00) | EPHX2FAAHNPC1RAB9A | |
| SCHEMBL3191093 | 0.86 | EPHX2 (0.88) | EPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662910-B2 | Inhibitors for the soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-16 | — | — | US | claimed |