⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987586 | 0.76 | — | — | |
| SCHEMBL28076039 | 0.72 | — | — | |
| SCHEMBL8927850 | 0.69 | — | — | |
| SCHEMBL7101727 | 0.67 | — | — | |
| SCHEMBL28156221 | 0.65 | — | — | |
| SCHEMBL3648196 | 0.65 | — | — | |
| SCHEMBL7632781 | 0.65 | — | — | |
| SCHEMBL25524339 | 0.65 | — | — | |
| SCHEMBL28628386 | 0.64 | — | — | |
| SCHEMBL29807506 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7648966-B2 | Mannose-6-phosphonate compounds for the treatment of inflammatory diseases | Pharmaxis Pty Limited (AU) | 2010-01-19 | — | — | US | disclosed |
| EP-1628987-B1 | MANNOSE-6-PHOSPHONATE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | PHARMAXIS PTY LTD (AU) | 2009-08-19 | — | — | EP | disclosed |
| US-20070082850-A1 | Mannose-6-phosphonate compounds for the treatment of inflammatory diseases | PHARMAXIX PTY LTD (AU) | 2007-04-12 | — | — | US | disclosed |
| EP-1628987-A2 | MANNOSE-6-PHOSPHONATE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | Pharmaxis Pty Ltd. (AU) | 2006-03-01 | — | — | EP | disclosed |
| WO-2004104015-A2 | MANNOSE-6-PHOSPHONATE COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISEASES | PHARMAXIS PTY LTD. (AU) | 2004-12-02 | — | — | WO | disclosed |