Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2742886 | 0.94 | FFAR1 (0.41) | FFAR1PPARGPPARDPOLBGAA | |
| SCHEMBL231550 | 0.90 | FFAR1 (0.47) | FFAR1PPARGPPARDSCN9ALMNA | |
| SCHEMBL317732 | 0.86 | FFAR1 (0.41) | FFAR1PPARG | |
| SCHEMBL16500085 | 0.84 | FFAR1 (0.43) | FFAR1PPARG | |
| SCHEMBL16500092 | 0.84 | FFAR1 (0.47) | FFAR1PPARG | |
| SCHEMBL2944400 | 0.80 | FFAR1 (0.43) | FFAR1PPARGPPARDSCN9ALMNA | |
| SCHEMBL16500102 | 0.79 | FFAR1 (0.50) | FFAR1PPARG | |
| SCHEMBL16500076 | 0.78 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL231420 | 0.77 | FFAR1 (0.61) | FFAR1 | |
| SCHEMBL231413 | 0.75 | FFAR1 (0.42) | FFAR1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590930-B1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI SA (FR) | 2015-02-25 | — | — | EP | disclosed |
| EP-2590930-A1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004270-A1 | SPIROCYCLICALLY SUBSTITUTED 1,3-PROPANE DIOXIDE DERIVATIVES, METHODS FOR THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENT | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |