SCHEMBL31808232

SCHEMBL31808232

COC(=O)c1cc2cc(F)ccc2s1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLK1 P49759 9/20 0.53
DYRK1A Q13627 5/20 0.52
CLK2 P49760 4/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
MAPT P10636 2/20 0.52
CLK4 Q9HAZ1 2/20 0.52
NPC1 O15118 1/20 0.52
RAB9A P51151 1/20 0.52
CHRNA7 P36544 3/20 0.48
HTR3A P46098 1/20 0.48
RPS6KB1 P23443 1/20 0.48
CSNK1D P48730 1/20 0.48
GSK3A P49840 1/20 0.48
GSK3B P49841 1/20 0.48
NTRK2 Q16620 1/20 0.48
AURKB Q96GD4 1/20 0.48
PTPN2 P17706 1/20 0.48
ALDH1A1 P00352 2/20 0.48
HPGD P15428 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL793053 1.00 CLK1 (0.53) CLK1DYRK1ACLK2MEN1KMT2A
SCHEMBL155481 0.87 HDAC1 (0.56) CLK1DYRK1ACLK2MEN1KMT2A
SCHEMBL11302733 0.83 PTPN2 (0.52) CLK1DYRK1ACLK2MEN1KMT2A
SCHEMBL2897390 0.83 BCL2L1 (0.59) CLK1DYRK1ACLK2MEN1KMT2A
SCHEMBL29742282 0.83 BCL2L1 (0.59) CLK1DYRK1ACLK2MEN1KMT2A
SCHEMBL2895953 0.82 MEN1 (0.64) CLK1DYRK1ACLK2MEN1KMT2A
SCHEMBL3641925 0.82 DYRK1A (0.68) CLK1DYRK1AMEN1KMT2AMAPT
SCHEMBL15697489 0.82 HDAC1 (0.61) CLK1DYRK1AMEN1KMT2AMAPT
SCHEMBL31108990 0.82 MEN1 (0.64) CLK1DYRK1ACLK2MEN1KMT2A
SCHEMBL17988510 0.81 CLK1 (0.67) CLK1DYRK1ACLK2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090589-A1 HETEROCYCLIC HBS1L DEGRADERS TANGO THERAPEUTICS, INC. (US) 2026-04-30 WO disclosed