Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3749476 | 0.92 | EPHX2 (0.35) | EPHX2PTGESKITHDAC1HDAC8 | |
| SCHEMBL318197 | 0.89 | EPHX2 (0.37) | EPHX2NR1H4PTGESP2RX7 | |
| SCHEMBL318073 | 0.85 | EPHX2 (0.35) | EPHX2NR1H4P2RX7ALDH1A1 | |
| SCHEMBL318019 | 0.84 | EPHX2 (0.40) | EPHX2NR1H4 | |
| SCHEMBL318389 | 0.83 | EPHX2 (0.33) | EPHX2NR1H4PTGESP2RX7 | |
| SCHEMBL318477 | 0.83 | EPHX2 (0.34) | EPHX2NR1H4 | |
| SCHEMBL926057 | 0.80 | EPHX2 (0.35) | EPHX2NR1H4MAPTPOLB | |
| SCHEMBL2697871 | 0.80 | NOTUM (0.34) | EPHX2NR1H4 | |
| SCHEMBL318968 | 0.79 | BACE1 (0.34) | EPHX2NR1H4PTGESP2RX7 | |
| SCHEMBL319713 | 0.78 | EPHX2 (0.37) | EPHX2NR1H4PTGESP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004326-A1 | PESTICIDAL PYRROLINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2012-01-12 | — | — | WO | disclosed |