SCHEMBL3181386

SCHEMBL3181386

O=C(O[C@H]1CO[C@H]2[C@@H]1OC[C@H]2O)c1ccccc1O

nearest known ligand 0.70

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ BCHE P06276 16/20 0.70
▸ CES2 O00748 1/20 0.63
▸ MAPT P10636 1/20 0.43
▸ LMNA P02545 2/20 0.41
▸ TSHR P16473 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ CYP3A4 P08684 1/20 0.41
▸ CYP1A2 P05177 1/20 0.41
▸ CYP2C9 P11712 1/20 0.41
▸ CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12860944 1.00 BCHE (0.70) BCHECES2MAPTLMNATSHR
SCHEMBL11298564 0.93 BCHE (0.80) BCHECES2LMNATSHRALDH1A1
SCHEMBL11301171 0.86 BCHE (0.74) BCHECES2LMNATSHRALDH1A1
SCHEMBL13418839 0.86 BCHE (0.74) BCHECES2LMNATSHRALDH1A1
SCHEMBL15442485 0.86 BCHE (0.70) BCHECES2
SCHEMBL15442484 0.85 BCHE (0.73) BCHECES2LMNATSHRALDH1A1
SCHEMBL4382472 0.81 BCHE (0.68) BCHECES2
SCHEMBL13574473 0.81 BCHE (0.68) BCHECES2
SCHEMBL1157071 0.81 BCHE (0.68) BCHECES2
SCHEMBL18631352 0.81 BCHE (0.68) BCHECES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2665775-B1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC GLOBAL TECHNOLOGIES BV (NL) 2016-11-16 — — EP disclosed
US-8633265-B2 UV stabilization of isosorbide polycarbonates SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-01-21 — — US disclosed
EP-2665775-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC Innovative Plastics IP B.V. (NL) 2013-11-27 — — EP disclosed
EP-2203501-B1 ISOSORBIDE-BASED POLYCARBONATES, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2012-08-15 — — EP disclosed
WO-2012098513-A1 UV STABILIZATION OF ISOSORBIDE POLYCARBONATES SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2012-07-26 — — WO disclosed
US-20120184651-A1 UV Stabilization of Isosorbide Polycarbonates SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-07-19 — — US disclosed
US-7786246-B2 Isosorbide-based polycarbonates, method of making, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-08-31 — — US disclosed
EP-2203501-A1 ISOSORBIDE-BASED POLYCARBONATES, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM Sabic Innovative Plastics IP B.V. (NL) 2010-07-07 — — EP disclosed
US-20100099832-A1 ISOSORBIDE-BASED POLYCARBONATES, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-04-22 — — US disclosed
US-7671164-B2 Aliphatic polycarbonates, methods of making, and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-03-02 — — US disclosed
US-7666972-B2 Isosorbide-based polycarbonates, method of making, and articles formed therefrom SABIC Innovative Plastics IP B., V. (NL) 2010-02-23 — — US disclosed
US-20090105393-A1 ISOSORBIDE-BASED POLYCARBONATES, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-04-23 — — US disclosed
US-20090105443-A1 ALIPHATIC POLYCARBONATES, METHODS OF MAKING, AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-04-23 — — US disclosed
WO-2009052463-A1 ISOSORBIDE-BASED POLYCARBONATES, METHOD OF MAKING, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS I.P. B.V. (NL) 2009-04-23 — — WO disclosed
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