SCHEMBL318148

SCHEMBL318148

CCCCCCCCCCCCCCCCCCCCCCOc1ccc(/C=N/O)c(OCCCCCCCCCCCCCCCCCCCCCC)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
NR5A1 Q13285 1/20 0.47
RAB9A P51151 2/20 0.47
TP53 P04637 2/20 0.47
MAPT P10636 2/20 0.47
NPC1 O15118 1/20 0.47
LMNA P02545 1/20 0.47
GAA P10253 1/20 0.47
ALOX15 P16050 1/20 0.47
HSD17B10 Q99714 1/20 0.47
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
NPY1R P25929 1/20 0.45
NPY2R P49146 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
TSHR P16473 4/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL318149 1.00 HPGD (0.49) HPGDMEN1KMT2ANR5A1RAB9A
SCHEMBL31111418 1.00 HPGD (0.49) HPGDMEN1KMT2ANR5A1RAB9A
SCHEMBL28212995 0.86 NR5A1 (0.55) MEN1KMT2ANR5A1RAB9ATP53
SCHEMBL28212996 0.86 NR5A1 (0.55) MEN1KMT2ANR5A1RAB9ATP53
SCHEMBL3297164 0.86 NR5A1 (0.55) MEN1KMT2ANR5A1RAB9ATP53
SCHEMBL3297166 0.86 NR5A1 (0.55) MEN1KMT2ANR5A1RAB9ATP53
SCHEMBL7561057 0.83 NR5A1 (0.51) HPGDMEN1KMT2ANR5A1RAB9A
SCHEMBL7561060 0.83 NR5A1 (0.51) HPGDMEN1KMT2ANR5A1RAB9A
SCHEMBL5075324 0.82 HPGD (0.58) HPGDMEN1KMT2ARAB9AMAPT
SCHEMBL5072961 0.82 HPGD (0.58) HPGDMEN1KMT2ARAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293948-B2 Reagent for organic synthesis and method of organic synthesis reaction with the reagent JITSUBO CO., LTD. (JP) 2012-10-23 US disclosed
US-20120108788-A1 REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT JITSUBO CO., LTD. (JP) 2012-05-03 US disclosed
US-8093435-B2 Reagent for organic synthesis and method of organic synthesis reaction with the reagent JITSUBO CO., LTD. (JP) 2012-01-10 US disclosed
US-20090299103-A1 Reagent for Organic Synthesis and Method of Organic Synthesis Reaction with the Reagent NATIONAL UNIVERSITY CORPORATION, TOKYO UNIVERSITY (JP) 2009-12-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299103-A1 Reagent for Organic Synthesis and Method of Organic Synthesis Reaction with the Reagent COASY, OSTC, OGA HPGD 2148/4885MEN1 2088/4885KMT2A 1686/4885
US-20120108788-A1 REAGENT FOR ORGANIC SYNTHESIS AND METHOD OF ORGANIC SYNTHESIS REACTION WITH THE REAGENT COASY, OSTC, OGA HPGD 2148/4885MEN1 2088/4885KMT2A 1686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.